Snakeroot is a common name that can refer to several different plants, but most often it refers to Rauwolfia serpentina (Indian snakeroot) or Aristolochia serpentaria (Virginia snakeroot). The use of snakeroot, especially Rauwolfia serpentina, in supporting the heart body system is primarily rooted in traditional medicine. In Ayurvedic medicine, Indian snakeroot has been used for centuries as a remedy for hypertension and other circulatory disorders. The roots contain alkaloids such as reserpine, which were later isolated and used as some of the earliest pharmaceutical treatments for high blood pressure and certain psychiatric conditions.

While the traditional use is well documented, scientific validation is mixed and primarily historical. Reserpine was widely prescribed in the mid-20th century as an antihypertensive agent, but its use has declined due to side effects and the availability of newer, safer medications. There is limited evidence from modern clinical trials, but historical pharmacological data and traditional texts support its heart-related use. Other plants called "snakeroot" (such as Aristolochia serpentaria) do not have strong scientific or traditional ties to cardiovascular support and may even be toxic.

In summary, the support for snakeroot in heart health is primarily traditional, with some historical scientific validation specific to Rauwolfia serpentina. However, safety concerns and the specificity of plant species should be carefully considered.