Evidence supporting the use of: Bicarbonate (mixed)
For the health condition: Hangover

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Bicarbonate (often sodium bicarbonate, or "baking soda") has a traditional history of use as a "home remedy" for hangovers, typically in the form of effervescent antacid solutions or as an ingredient in over-the-counter hangover powders. The reasoning behind its use is that bicarbonate can help neutralize stomach acid, addressing symptoms like nausea or indigestion commonly experienced during a hangover. However, there is minimal to no direct scientific evidence that bicarbonate addresses the primary causes of hangover, which include dehydration, acetaldehyde accumulation, and inflammation. Research has not established that altering blood or gastric pH with bicarbonate has any significant effect on the metabolism of alcohol or its toxic byproducts. Its use is mainly justified by anecdotal reports and longstanding tradition rather than randomized controlled trials or systematic scientific validation. As such, while bicarbonate may provide temporary relief for heartburn or upset stomach associated with hangover, it does not treat the underlying physiological effects of alcohol consumption, and excessive use can cause metabolic alkalosis or electrolyte imbalances. Thus, its evidence rating for treating hangover specifically is low.

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