Evidence supporting the use of: Quercetin
For the health condition: Hair (loss or thinning)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Quercetin is a plant flavonoid found in many fruits and vegetables and is known for its antioxidant and anti-inflammatory properties. Its use for supporting hair health, particularly in cases of hair loss or thinning, is based on emerging scientific evidence rather than longstanding traditional use. The scientific rationale centers on quercetin's ability to reduce oxidative stress and inflammation, both of which are thought to contribute to hair follicle damage and dysfunction. Some animal studies have suggested that quercetin can promote hair regrowth by modulating inflammatory pathways and supporting the anagen (growth) phase of the hair cycle. For example, research in mice has demonstrated that topical or oral quercetin may help reduce hair loss induced by certain stressors or autoimmune mechanisms, potentially by inhibiting pro-inflammatory cytokines such as TNF-α and IL-1β.

However, direct clinical evidence in humans is limited. Most available data are preclinical, and robust human trials are lacking. Quercetin is sometimes included in hair supplements for its general health benefits, but its efficacy for hair loss or thinning specifically cannot be considered strongly validated at this time. In summary, the use of quercetin for hair loss is primarily supported by early-stage scientific research, with a low-to-moderate evidence rating (2 out of 5) due to the lack of large-scale, high-quality human studies.

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