Amino acid chelates are minerals (such as zinc, iron, copper, or magnesium) bound to amino acids, which are claimed to improve mineral absorption and bioavailability. Their use in supporting hair health, particularly for hair loss or thinning, is based on the fact that certain mineral deficiencies (notably iron and zinc) are associated with hair loss. Scientific studies have shown that correcting these deficiencies can improve hair growth in individuals who are deficient, and amino acid chelates may be better absorbed than non-chelated forms. For example, iron amino acid chelates have been observed to raise iron levels efficiently in anemic patients, and zinc chelates may improve zinc status.

However, the evidence specifically supporting amino acid chelates (versus other forms of minerals) for hair loss is limited. Most clinical studies focus on overall mineral supplementation rather than chelated forms. No substantial research directly links amino acid chelate supplementation to improved hair growth or prevention of thinning in the absence of a diagnosed deficiency. Therefore, while the scientific rationale for using amino acid chelates to correct mineral deficiencies that can lead to hair loss is valid, the evidence for their use as a general hair loss treatment is weak. The rating reflects this gap between mechanistic plausibility and direct clinical evidence.