Vitamin B6 (pyridoxine) is often included in supplements marketed for hair health, as it is essential for numerous metabolic processes, including the synthesis of amino acids and proteins. Scientifically, vitamin B6 plays a role in the formation of keratin and melanin, which are important for hair structure and pigmentation. However, direct evidence linking vitamin B6 supplementation to improved hair growth or reduced hair loss in healthy individuals is limited. Most of the available research focuses on its role in addressing deficiencies, which can contribute to symptoms such as hair thinning or hair loss. For example, severe B6 deficiency, though rare, can lead to dermatological symptoms including hair changes. In these cases, correcting the deficiency can help restore hair health.

There is little robust clinical evidence that vitamin B6 supplementation benefits hair in people with normal nutritional status. Some small studies and anecdotal reports suggest a possible benefit when B6 is used in combination with other B vitamins (such as biotin or B12) for certain types of hair loss, but these findings are not consistent or widely validated. Thus, while there is a biological rationale and some scientific basis for using vitamin B6 to support hair health, the evidence supporting its effectiveness is moderate at best and primarily pertains to deficiency states.