Evidence supporting the use of: MSM (Methylsulfonylmethane)
For the body system: Hair
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Methylsulfonylmethane (MSM) is a sulfur-containing compound commonly found in dietary supplements marketed for hair, skin, and nail health. The rationale for its use in supporting the hair body system is primarily based on the role of sulfur in keratin, the key structural protein in hair. Several preliminary studies and small clinical trials suggest that MSM may have a positive effect on hair growth and quality. For instance, a double-blind, placebo-controlled study published in 2009 found that a supplement containing MSM and other ingredients improved hair shine and volume after 8 weeks, but the study did not isolate MSM as the sole active agent. Another pilot study in 2019 using topical MSM showed potential for increasing hair diameter, though the sample size was small.
Most human evidence remains limited and often includes MSM in combination with other nutrients, making it difficult to attribute effects specifically to MSM. Preclinical studies indicate that MSM provides the sulfur necessary for the formation of amino acids like methionine and cysteine, which are important for hair structure. While these mechanisms are plausible, robust, large-scale clinical trials on MSM alone are lacking. Therefore, the scientific evidence is suggestive but not strong, and the rating reflects the preliminary nature of current findings. MSM’s use for hair support is grounded more in emerging scientific investigation rather than established clinical practice or long-standing traditional use.
Other ingredients that support Hair
amino acidsashwagandha
bamboo
biotin
bovine gelatin
ceramides
collagen
copper
fish oil
fish protein
gamma linolenic acid (GLA)
gelatin
ginseng
gooseberry
gotu kola
horsetail
iron
kelp
l-cysteine
l-cystine
l-lysine
l-methionine
l-proline
methylsulfonylmethane (MSM)
nettle
omega-3 fatty acids
omega-6 fatty acids
PABA (para-aminobenzoic acid)
pantothenic acid (vitamin B5)
pollen
polypeptide complex (proprietary)
protein
pumpkin
riboflavin (vitamin B2)
rosemary
sage
saw palmetto
selenium
silicon
keratin
vitamin A
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin E
seaweed
zinc
zinc
lingzhi
sunflower
trace minerals
wheat germ
herbal blend (proprietary)
algae
bladderwrack
Argan nut oil
Alkanna
Animal protein
Black Seed
Babchi
Beef
Beef liver
Bovine Protein
Curry leaf
Cetearyl alcohol
Chinese Fleeceflower
Cymbopogon Martini
Castile Soap
Cystine
DL-Methionine
Drynaria
Egg
Eclipta
Emu Oil
Egg protein
Ferritin
Fo-Ti
Fish
Fatty acids
Garden Cress
Molasses
Quinoa Protein
Silk protein
silica