Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Oligomeric proanthocyanidins (OPCs) are a class of polyphenolic compounds found in foods such as grapes, cranberries, and pine bark. Their use for supporting gum (periodontal) health is primarily based on scientific evidence, though the body of research is still developing. In vitro and animal studies have demonstrated that OPCs possess potent antioxidant and anti-inflammatory properties, which are beneficial for oral tissues. Specifically, OPCs have been shown to inhibit the growth of oral pathogens such as Porphyromonas gingivalis, a key bacterium involved in periodontal disease. OPCs also help stabilize collagen, an important protein in gum tissue, and may promote tissue repair.

Some small clinical studies suggest that OPC supplementation can reduce signs of gingival inflammation and bleeding in individuals with gum disease. For instance, pine bark extract (rich in OPCs) has been reported to improve periodontal parameters such as bleeding on probing and pocket depth when used as an adjunct to conventional dental care. However, more large-scale, high-quality clinical trials are needed to draw definitive conclusions regarding effectiveness and optimal dosing. Overall, while traditional use is limited, the scientific evidence provides a moderate level of support for OPCs in promoting gum health.

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