Evidence supporting the use of: Flavonols
For the body system: Gums

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flavonols are a subclass of flavonoids, a group of polyphenolic compounds found abundantly in fruits, vegetables, tea, and other plant-based foods. There is a growing body of scientific evidence suggesting that flavonols may benefit gum (periodontal) health primarily due to their antioxidant and anti-inflammatory properties. Several studies have shown that flavonol-rich foods and extracts, such as those containing quercetin, kaempferol, and myricetin, can inhibit the growth of oral pathogens associated with periodontal disease and reduce inflammation of gum tissues. For instance, some in vitro and animal studies demonstrate that flavonols can suppress the activity of bacteria like Porphyromonas gingivalis, a key contributor to periodontitis, and modulate the host’s inflammatory response, leading to less tissue destruction.

Clinical evidence in humans, while still emerging, provides preliminary support for flavonols' role in maintaining gum health. Some small-scale clinical trials and observational studies have found associations between higher intake of flavonol-rich foods and reduced risk or severity of periodontal disease. However, the quality and size of these studies are variable, and more robust randomized controlled trials are needed to establish definitive efficacy. Overall, the use of flavonols for supporting gum health is justified by scientific evidence, though it remains an area of active research rather than established clinical practice.

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Products containing flavonols

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