Evidence supporting the use of: Flavonoids
For the body system: Gums

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flavonoids are a diverse group of phytonutrients found in many fruits, vegetables, and herbs, and they have been studied for their potential benefits in oral health, particularly in supporting gum (periodontal) health. Scientific evidence suggests that flavonoids exhibit anti-inflammatory, antioxidant, and antimicrobial properties, which can be beneficial for the gums. Several in vitro and in vivo studies have demonstrated that flavonoids can inhibit the growth of periodontal pathogens and reduce inflammation in gum tissues.

For example, research has shown that flavonoids such as quercetin, catechins (from green tea), and hesperidin can suppress the production of pro-inflammatory cytokines and decrease oxidative stress in the gums. A 2016 review in the Journal of Clinical and Diagnostic Research noted that flavonoids have the potential to prevent or ameliorate periodontal diseases by reducing inflammation and supporting the body's natural defense mechanisms in oral tissues. Additionally, some clinical trials have observed improvements in gum bleeding and reduction in plaque when using flavonoid-containing oral care products.

While the evidence is promising, much of it is preclinical or from small clinical studies. More large-scale, well-controlled human trials are needed to fully confirm the effectiveness of flavonoids in gum health. Overall, there is a scientific rationale for using flavonoids to support the gums, but the strength of evidence is moderate rather than definitive.

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