Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Prunus species (such as Prunus domestica, Prunus cerasus, and others) have a history of use in traditional medicine systems for the management of gout and related symptoms. This traditional use is largely based on ethnobotanical records, especially in European and Asian herbal medicine, where extracts or preparations from the fruit, bark, or leaves have been used as diuretics or to "cleanse the blood." The rationale in traditional practice is often linked to the presumed ability of Prunus species to support kidney function and promote uric acid excretion, thereby alleviating gout symptoms.

However, scientific validation for these uses is limited. Some modern studies have investigated the effects of certain Prunus fruits, such as cherries (Prunus avium and Prunus cerasus), on serum uric acid levels and inflammation. There is modest evidence that cherry consumption may reduce the frequency of gout attacks, but these studies typically focus on specific species and forms (not unspecified Prunus), and the quality of evidence is still considered preliminary. There is little to no robust clinical data for most Prunus species or unspecified preparations regarding gout. Thus, while the traditional use is well documented, scientific support is weak and mostly limited to particular species with potential anti-inflammatory or uricosuric effects.

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