Five-leaf akebia (Akebia quinata), known as "mu tong" in traditional Chinese medicine (TCM), has been used historically for a variety of conditions, including promoting urination and alleviating pain. Its application for treating or supporting gout is largely based on its traditional use as a diuretic and its purported ability to clear "damp-heat" from the body, which in TCM theory is thought to contribute to gout symptoms such as swelling and joint pain. However, there is a lack of robust clinical data or pharmacological studies directly linking Five-leaf akebia to effective treatment or management of gout. The traditional use does not specifically target the uric acid lowering or anti-inflammatory mechanisms that are central to modern gout therapy. While some in vitro or animal studies have explored the plant's anti-inflammatory or diuretic effects, these do not constitute direct evidence for efficacy in gout in humans. As such, its use for gout is mainly justified by tradition, and current scientific evidence supporting its effectiveness in this context remains extremely limited.