Evidence supporting the use of: Indigo leaves
For the health condition: Gonorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Indigo leaves, particularly from the species Indigofera tinctoria and related plants, have a longstanding history in traditional medicine across parts of Africa and Asia. In ethnobotanical records, these leaves have been used in decoctions or pastes for the treatment of sexually transmitted infections such as gonorrhea. The rationale for their use is primarily based on their reported antimicrobial properties and the empirical observations of traditional healers. In some cultures, the leaves are prepared as a wash or taken orally, often in combination with other herbs. While there are some preliminary laboratory studies indicating that extracts of indigo leaves may exhibit antibacterial activity, these studies are typically in vitro (outside the body) and do not specifically address Neisseria gonorrhoeae, the causative agent of gonorrhea. Moreover, there are no robust clinical trials or pharmacological studies in humans that validate the efficacy or safety of indigo leaves for this infection. Thus, the use of indigo leaves for gonorrhea is justified primarily by traditional practices rather than scientific validation, and the evidence is limited, rating a 2 on the scale provided. Caution is advised, as reliance on traditional remedies alone without proven efficacy may delay effective treatment and increase the risk of complications.

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