Synopsis

Source of validity: Traditional
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Commiphora gileadensis, commonly known as balm of Gilead, has a long-standing history in traditional medicine systems of the Middle East and North Africa. Ethnobotanical records indicate its use for various infectious and inflammatory conditions, including sexually transmitted infections such as gonorrhea. Traditional healers have used the resin and extracts of this plant for their presumed antimicrobial and anti-inflammatory properties. However, scientific investigation into its efficacy specifically against Neisseria gonorrhoeae, the causative agent of gonorrhea, is extremely limited. Only general antimicrobial activity has been reported for related species in the genus Commiphora, and there are no robust clinical trials or laboratory studies directly supporting its effectiveness for gonorrhea in humans. Thus, its use for this condition remains primarily justified by traditional practice rather than scientific validation. The available evidence is anecdotal and based on historical texts and ethnopharmacological surveys rather than modern clinical research.

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