Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Abrus, typically referring to Abrus precatorius (commonly known as jequirity, rosary pea, or crab's eye), has a history of use in traditional medicine systems, particularly in Ayurveda and African folk medicine. There are ethnobotanical reports documenting the use of various parts of the Abrus plant, such as leaves and roots, in formulations intended to address sexually transmitted infections, including gonorrhea. The traditional rationale is based on the plant’s reputed antimicrobial and anti-inflammatory properties, which practitioners believed could help alleviate symptoms or potentially treat the underlying infection. However, the evidence for its efficacy is limited to anecdotal and historical accounts, with no rigorous clinical trials or well-designed preclinical studies demonstrating clear anti-gonococcal activity. Moreover, the plant contains abrin, a highly toxic protein, which poses significant safety risks and limits its practical use. Scientific validation of its use for gonorrhea is lacking, and modern medical guidance does not support Abrus for this indication. In summary, while Abrus has been traditionally used in some cultures for treating gonorrhea, the supporting evidence is weak, and its use is not recommended due to toxicity concerns and insufficient scientific backing.

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