Evidence supporting the use of: Trichosanthes
For the health condition: Goiter

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Trichosanthes, particularly Trichosanthes kirilowii and related species, has a longstanding place in traditional Chinese medicine (TCM). Historically, its root (known as Tian Hua Fen) has been used to address various "phlegm" disorders, which in TCM theory includes goiter ("Ying"). Ancient texts such as the Shennong Bencao Jing and later materia medica describe Trichosanthes as being used to "dissolve masses" and "clear heat," indirectly indicating its recommendation for thyroid swellings like goiter. However, this use is primarily based on traditional pattern recognition and symptom management rather than an understanding of thyroid function or iodine metabolism.

Scientific research directly supporting Trichosanthes for goiter is extremely limited. There are a few preclinical studies on trichosanthin (a protein from the plant) revealing antitumor or immunomodulatory effects, but no robust clinical trials have confirmed efficacy for thyroid enlargement or dysfunction. Furthermore, goiter is now known to be largely related to iodine deficiency or autoimmune conditions, and there is no evidence that Trichosanthes addresses these root causes.

In summary, while there is a clear traditional basis for the use of Trichosanthes in treating goiter within TCM, modern scientific evidence is lacking, and the traditional rationale does not align with contemporary understanding of the disease etiology.

More about trichosanthes
More about Goiter