Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Physalis angulata, commonly known as cutleaf groundcherry, has been used in various traditional medicine systems, particularly in tropical regions. In some folk remedies, parts of the plant have been applied to swellings and glandular enlargements, which may include goiter (an enlargement of the thyroid gland). However, the documentation of its specific use for goiter is sparse and primarily anecdotal, based on ethnobotanical surveys rather than controlled studies. There is no robust scientific literature that validates its efficacy for the treatment or management of goiter, nor are there any well-characterized bioactive compounds from Physalis angulata specifically linked to thyroid function or disorders. The traditional application appears to stem from its general anti-inflammatory and purported "gland-reducing" properties rather than any targeted effect on thyroid health. In summary, while Physalis angulata has a history of use in traditional medicine for various ailments, including possible applications for swellings labeled as goiter, there is minimal scientific evidence to support its use for this condition, and the available traditional evidence is weak and non-specific.

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