Lophatherum leaf (Lophatherum gracile), also known as "Danzhuye" in Traditional Chinese Medicine (TCM), is primarily used in East Asian herbal traditions. In TCM, it is considered to have cooling and diuretic properties and is commonly used to "clear heat" and promote urination. While it is most often associated with supporting the urinary system and addressing symptoms such as fever, irritability, and thirst, there is some traditional rationale for its use in supporting the glandular system, particularly as it relates to regulating fluids and addressing heat conditions thought to involve glands (such as lymphatic tissues or sweat glands).

However, there is little to no robust scientific research specifically validating Lophatherum leaf for direct glandular system support—such as for endocrine glands like the thyroid, adrenal, or pituitary. Most references to its use are found in historical texts and herbal compendia, and any reported effects on the glands are based on TCM theory rather than modern physiological or clinical studies. Therefore, while the ingredient is traditionally used for general "heat-clearing" and fluid regulation (which may be interpreted as affecting glandular function in a broad sense), there is insufficient evidence from controlled studies to confirm specific glandular system benefits.