Evidence supporting the use of: Insulin-like growth factor
For the body system: Glandular System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Insulin-like growth factor (IGF), particularly IGF-1, is a hormone with a structure similar to insulin and plays a crucial role in childhood growth and continues to have anabolic effects in adults. The glandular system includes organs such as the pituitary, thyroid, adrenal glands, and pancreas, all of which are involved in hormone production and regulation. IGF-1 is primarily produced in the liver as a response to growth hormone (GH) stimulation and mediates many of GH's growth-promoting effects. There is scientific evidence supporting IGF-1’s involvement in the regulation and maintenance of the endocrine (glandular) system, particularly its interplay with the pituitary gland and its influence on tissue growth, metabolism, and cellular repair. IGF-1 supplementation or analogs have been investigated for use in conditions of growth hormone deficiency and for their potential to support tissue repair and regeneration. However, while there is evidence for IGF-1’s physiological role in glandular function, the clinical use of exogenous IGF-1 supplementation for general glandular system support in healthy individuals is not well established and may carry risks, such as promoting tumorigenesis or metabolic disturbances. Therefore, while the scientific basis for IGF-1's role in the glandular system is strong, routine supplementation is not widely endorsed outside specific medical indications.

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Products containing Insulin-like growth factor

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