Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Cruciferous vegetables, such as broccoli, cabbage, kale, and Brussels sprouts, are well-documented for their high content of phytochemicals, particularly glucosinolates. When consumed, these compounds are metabolized into biologically active substances like indole-3-carbinol and sulforaphane. There is scientific evidence suggesting that these metabolites can influence hormonal metabolism, particularly estrogen, through modulation of enzymes involved in hormone metabolism in the liver. This potential to modulate hormone levels is one reason why cruciferous vegetables are sometimes associated with supporting the glandular (endocrine) system, which includes hormone-producing glands such as the thyroid, adrenals, and reproductive glands.

Additionally, cruciferous vegetables have been studied for their possible protective effects against hormone-related cancers, such as those of the breast and prostate, lending indirect support to the notion that they influence glandular or hormonal health. However, while these findings are promising, direct clinical evidence supporting the use of unspecified cruciferous vegetables as a supplement specifically targeting the glandular system is limited. Most of the research focuses on dietary intake rather than supplementation, and the effects on specific glands (other than the thyroid, where excessive intake may actually be problematic in some individuals) are not fully elucidated. Therefore, the scientific basis is moderate but not robust, justifying a score of 3 out of 5.

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