Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Anemarrhena asphodeloides, known as "zhi mu" in traditional Chinese medicine (TCM), has a long history of use for addressing imbalances in the body's glandular or endocrine systems, particularly in relation to symptoms associated with "yin deficiency." In TCM, this herb is believed to nourish yin, clear heat, and moisten dryness—functions sometimes interpreted in Western terms as supporting hormonal balance or glandular health. It has been used in formulas to address symptoms such as night sweats, hot flashes, and irritability, which are thought to relate to hormonal or glandular disturbances. However, scientific studies specifically validating its effects on the human glandular or endocrine system are limited and largely preclinical or animal-based. Some research has investigated its saponins (such as timosaponin) for potential anti-diabetic, anti-inflammatory, and neuroprotective effects, but robust clinical evidence for direct glandular system support in humans is lacking. Therefore, its use for supporting the glandular system is primarily rooted in traditional practice, and the available evidence is best rated as 2 out of 5—indicating traditional use with some suggestive but not conclusive scientific findings.

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