Evidence supporting the use of: Artemisia (unspecified)
For the health condition: Giardia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Artemisia species, particularly Artemisia annua and Artemisia absinthium, have a history of traditional use for treating intestinal parasites, including Giardia infections. In addition to this traditional use, there is some scientific evidence supporting the efficacy of Artemisia extracts against Giardia lamblia (also known as Giardia intestinalis). Laboratory (in vitro) studies have demonstrated that extracts from Artemisia annua and Artemisia absinthium possess significant anti-giardial activity, inhibiting the growth and survival of the parasite. In vivo studies in animal models, such as mice, have also shown reduced Giardia infection following treatment with Artemisia extracts. The mechanism is thought to involve the presence of sesquiterpene lactones, such as artemisinin and related compounds, which disrupt key metabolic pathways in the parasite. However, clinical trials in humans are limited. A small number of clinical studies and case reports suggest potential benefit, but the evidence is not robust or widespread enough to warrant broad clinical recommendations. Most human studies have been small, not always placebo-controlled, and often combine Artemisia with other anti-parasitic herbs, making it difficult to attribute efficacy to Artemisia alone. Safety concerns also remain, especially regarding long-term or high-dose use. In summary, use of Artemisia for Giardia is based on both tradition and emerging scientific evidence, but more rigorous human studies are needed to confirm efficacy and safety.

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