Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Microbial enzymes are increasingly used in dietary supplements to support digestive health, particularly for symptoms such as gas and bloating. The rationale for their use is grounded in scientific understanding of how specific enzymes facilitate the breakdown of complex carbohydrates, proteins, and fats that, when not properly digested, can lead to gastrointestinal discomfort. Microbial enzymes, produced by fermentation of specific fungi or bacteria (e.g., Aspergillus oryzae, Aspergillus niger), include amylase, protease, lipase, cellulase, and lactase, among others. These enzymes are active across a broad pH range and are effective in the human gastrointestinal tract. Clinical studies have shown that supplementation with microbial-derived enzymes, particularly alpha-galactosidase and lactase, can reduce symptoms of gas and bloating in individuals who have difficulty digesting certain carbohydrates (like beans, cruciferous vegetables, or lactose-containing foods). For example, alpha-galactosidase has been found to significantly decrease hydrogen gas production and abdominal symptoms in individuals consuming high-fiber meals. Similarly, lactase supplements help reduce bloating and discomfort in lactose-intolerant individuals. While there is robust evidence for specific enzymes, proprietary blends may vary in composition and activity, so product efficacy can differ. Nevertheless, the scientific consensus supports the use of microbial enzymes for alleviating gas and bloating, especially in populations with known digestive enzyme deficiencies or sensitivities.

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