Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Isomalto-oligosaccharide (IMO) is a type of prebiotic fiber that has been explored for its effects on digestive health, including gas and bloating. The scientific rationale for IMO's use is based on its ability to modulate gut microbiota. Prebiotics like IMO can promote the growth of beneficial bacteria such as Bifidobacterium and Lactobacillus, which theoretically may improve gut health and potentially reduce symptoms of bloating over time. However, the evidence specifically supporting IMO for gas and bloating is limited and mixed. Some studies suggest that IMO is less fermentable than other fibers, potentially causing less gas production, while others report increased gas and bloating, especially in sensitive individuals or at higher doses.

A handful of small clinical trials and in vitro studies have examined IMO's effects, but results are inconsistent, and studies often use surrogate endpoints (like microbiome composition) rather than direct measures of bloating or gas. Some users report increased bloating initially, as the gut adapts to increased fiber, which may subside with regular use. As such, while IMO is sometimes included in digestive health supplements marketed for bloating, robust clinical evidence directly supporting its efficacy for this specific symptom is lacking. Therefore, the level of scientific evidence specifically for gas and bloating is rated as low (2/5), and more research is needed to clarify its effectiveness and tolerance profile.

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Products containing isomalto-oligosaccharide

Nature's Sunshine Stixated
Nature's Sunshine Stomach Comfort (Chewable)