Evidence supporting the use of: Cynarin
For the health condition: Gall Bladder (sluggish or removed)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Cynarin is a compound found primarily in artichoke (Cynara scolymus) and has a long history of traditional use in European herbal medicine for supporting liver and gall bladder health. Traditional herbalists have used artichoke extracts, including cynarin, as a choleretic—meaning it is believed to stimulate the production and flow of bile from the liver and gall bladder. This use is rooted in folk medicine practices aimed at relieving symptoms of indigestion, "sluggish" gall bladder, and to support digestion after gall bladder removal. Scientifically, there is some evidence from animal and in vitro studies that cynarin and artichoke extracts can increase bile secretion. A few small human studies have also indicated improved bile flow and mild benefits for digestion. However, robust clinical trials specifically assessing cynarin for gall bladder dysfunction or post-cholecystectomy support are limited. The European Medicines Agency acknowledges traditional use of artichoke leaf for "supportive treatment of dyspeptic complaints." Overall, the use of cynarin for gall bladder support is primarily justified by tradition, with some preliminary scientific findings but lacking strong, high-quality clinical evidence. Its use after gall bladder removal is based on the rationale of supporting bile production, but direct evidence for this application is minimal. Thus, the strength of evidence is modest.
More about Cynarin
More about Gall Bladder (sluggish or removed)
Other ingredients used for Gall Bladder (sluggish or removed)
appleartichoke
barberry
beet
bovine
bupleurum falcatum
burdock
chicory
turmeric
dandelion
ginger
horseradish
lemon
licorice root
lipase
milk thistle
mustard seed
oregon grape
ox bile
pancreatin
parsley
pear
phellodendron amurense
phosphatidylcholine
silymarin
triphala
atractylodes
papaya
Indian bael
punarnava
fumaria parviflora
peony
goldenrod
bile salt
myrrh
cornsilk
birch
couch grass
cleavers
enzymes blend (proprietary)
Avens
Angelica
American Liverleaf
Brassica
Berberis (unspecified)
Bitter Grass
boldo
Baccharoides anthelmintica
Bur-Reed
Bile
Black Nightshade
Bitter principals
bile acid
Bupleurum
Boerhavia diffusa
cholic acid
Carqueja
Cynarin
Costus
Castor Oil
Colocynth
Dianthus
Duodenal Substance
Dehydrocholic acid
Endive
Fiber
Fumitory
Hedyotis
Other health conditions supported by Cynarin
Cholesterol (high)Cirrhosis of the Liver
Fatty Liver Disease
Gall Bladder (sluggish or removed)
Gall Stones
Liver Detoxification
Triglycerides (high)