Evidence supporting the use of: Melaleuca alternifolia
For the health condition: Fungal Infections
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Melaleuca alternifolia, commonly known as tea tree oil, is supported by scientific evidence for its use in treating and supporting fungal infections. Numerous in vitro studies have demonstrated that tea tree oil possesses strong antifungal properties against a variety of pathogenic fungi, including Trichophyton species (responsible for athlete’s foot and nail fungus), Candida albicans (a common cause of oral and vaginal yeast infections), and other dermatophytes. The primary active component, terpinen-4-ol, has been shown to disrupt fungal cell membranes, leading to the destruction of the pathogen.
Several clinical trials provide moderate to strong evidence for tea tree oil’s efficacy, particularly for superficial fungal infections. For example, randomized controlled trials have shown that topical tea tree oil preparations can be as effective as conventional antifungal agents in treating athlete’s foot (tinea pedis) and onychomycosis (nail fungus), though results can vary depending on formulation and concentration. Furthermore, the oil has a long history of traditional use by indigenous Australians for treating skin infections, which supports its historical application.
However, while laboratory and clinical evidence is compelling for topical use, tea tree oil should not be ingested due to toxicity concerns. Overall, the evidence base rates at a 4 out of 5, as some studies have methodological limitations, but the majority confirm significant antifungal activity, especially for dermatological applications.
More about melaleuca alternifolia
More about Fungal Infections
Other ingredients used for Fungal Infections
ajoenealoe vera
alpha-pinene
barberry
basil
beta-pinene
bisabolol
black walnut
caprylic acid
chamomile
cinnamon
turmeric
goldenseal
green tea
lactoperoxidase
lauric acid
monolaurin
oregano
oregon grape
phenolic acids
rosemary
sage
schizonepeta
undecylenic acid
neem tree
nut grass
commiphora
caesalpinia crista
pau d'arco
lemongrass
morinda
oriental arborvitae
zanthoxylum
polyphenols
eucalyptus
camphor oil
menthol oil
melaleuca alternifolia
geranium
10-Undecenoic Acid
3-Phenyllactic Acid
Agarikon Mushroom
Alpha-terpineol
Ardisia
Allicin
Anamu
Ajuga
Ampelopsis
Allyl Sulfide
allyl isothiocyanate
Allium tuberosum
Alantolactone
Bee Propolis
Babchi
Baphicacanthus cusia
Barleria
Brazillian peppertree
Bisabolene
Bee hive
Borate
Black Nightshade
benzyl isothiocyanate
Borneol
Curry leaf
Caryophyllene
Calendula
Cinnamomum
coconut oil
Carvacrol
Cajuput
Citral
Centipeda
Chalcone
Copaiba Oil
Citronella
Dianthus
Euphorbia
Eugenol
Garlic
Mustard
Sandalwood
Sumac
Other health conditions supported by melaleuca alternifolia
AbrasionsAbscesses
Acne
Antibiotics (alternatives to)
Athlete's Foot
Bites and Stings
Blisters
Boils
Burns and Scalds
Cuts
Dandruff
Dermatitis
Ear Infection or Earache
Eczema
Fungal Infections
Gingivitis
Herpes
Impetigo
Insect Repellant
Itching
Jock Itch
Lice
Oral Surgery
Psoriasis
Rashes and Hives
Scabies
Scratches and Abrasions
Skin (infections)
Skin (oily)
Staph Infections
Stye
Sunburn
Thrush
Ulcerations (external)
Warts
Wounds and Sores