Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Caesalpinia crista has been traditionally used in various systems of medicine, such as Ayurveda and Unani, for the treatment of a variety of ailments, including fungal infections. Ethnobotanical records and traditional healers have described its seeds and extracts as useful for skin diseases, which often include infections of fungal origin. Several folklore remedies from India and Southeast Asia mention its application for ringworm and other dermal infections. However, the scientific validation for these uses is limited. There are some preliminary in vitro studies suggesting that extracts of Caesalpinia crista possess antifungal activity against certain pathogenic fungi, such as Aspergillus and Candida species, but these studies are not extensive, and clinical trials in humans are lacking. The antifungal effect is thought to be due to phytoconstituents like flavonoids, saponins, and diterpenes, which may inhibit fungal growth. Overall, while there is a traditional basis for using Caesalpinia crista for fungal infections and some weak in vitro evidence, high-quality scientific studies are needed to confirm its efficacy and safety for this purpose. Thus, its use is primarily justified by tradition rather than strong scientific evidence.

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