Evidence supporting the use of: Brazillian peppertree
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Brazilian peppertree (Schinus terebinthifolia) has a history of traditional use in South American medicine, but its application for fungal infections is increasingly supported by scientific research. In vitro studies have demonstrated that extracts from the leaves, bark, and fruits of the plant possess antifungal activity against a variety of pathogenic fungi, including Candida species and Aspergillus species. These effects are attributed to compounds such as essential oils, terpenes, and phenolic compounds present in the plant. For example, a 2018 systematic review (PubMed:29939388) found that various extracts of S. terebinthifolia showed inhibitory actions against dermatophytes and yeasts in vitro. However, while laboratory studies provide promising data, there is a lack of robust clinical trials in humans confirming its efficacy and safety for treating fungal infections. Most studies to date have been conducted in vitro or in animal models, and the translation of such results to clinical effectiveness remains uncertain. Thus, while there is a scientific basis for its antifungal properties, more high-quality clinical research is needed before Brazilian peppertree can be recommended as a reliable antifungal treatment in humans.

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