Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Baphicacanthus cusia (also known as Strobilanthes cusia or Qing Dai) has been traditionally used in Chinese medicine for a variety of conditions, including skin diseases such as eczema and psoriasis. Increasingly, there is scientific interest in its antifungal properties. Several in vitro studies have demonstrated that extracts from Baphicacanthus cusia possess antifungal activity against common pathogenic fungi, including Candida albicans and dermatophytes. The bioactive compounds thought to be responsible include indirubin, indigo, and other indole alkaloids. For example, a 2018 study published in the journal Phytotherapy Research found that ethanol extracts of Baphicacanthus cusia significantly inhibited the growth of several fungal strains in laboratory conditions. However, most evidence is limited to laboratory studies; there are very few controlled clinical trials assessing its efficacy in humans for fungal infections specifically. The traditional use in skin conditions, some of which are of fungal origin, provides indirect historical support. In conclusion, there is moderate scientific validation for the antifungal effects of Baphicacanthus cusia, but high-quality clinical evidence in humans is still lacking. More research, especially human trials, is needed to fully substantiate its therapeutic potential against fungal infections.

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