Evidence supporting the use of: Vitamin E (mixed tocotrienols/tocopherols)
For the health condition: Free Radical Damage

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin E, encompassing both tocopherols and tocotrienols, is widely recognized for its role as a lipid-soluble antioxidant. Its primary biological function is to protect cell membranes from oxidative damage caused by free radicals, specifically by interrupting the propagation of lipid peroxidation in cellular membranes. This mechanism has been validated through numerous in vitro, animal, and human studies, making Vitamin E one of the best-studied natural antioxidants.

The scientific evidence supporting Vitamin E’s use in mitigating free radical damage is substantial. Biochemical and clinical studies demonstrate that Vitamin E can reduce markers of oxidative stress in plasma, tissues, and cells. For example, supplementation with alpha-tocopherol has been shown to decrease levels of lipid peroxides and oxidized LDL cholesterol in the blood. Tocotrienols, though less studied than tocopherols, also exhibit potent antioxidant activity and may provide additional cellular protection.

However, while Vitamin E clearly mitigates free radical damage at the molecular and cellular level, the translation of these effects into clinical outcomes (such as prevention of chronic diseases) is less consistent. Large-scale clinical trials have yielded mixed results regarding its efficacy in reducing disease risk, leading to ongoing debate about the clinical relevance of antioxidant supplementation. Nonetheless, the antioxidant function of Vitamin E and its role in countering free radical damage at the biochemical level is well-established and supported by robust scientific evidence.

More about Vitamin E (mixed tocotrienols/tocopherols)
More about Free Radical Damage

Other ingredients used for Free Radical Damage

7-hydroxymatairesinol (HMR)
Acai berry
Acetyl L-carnitine
Alpha-carotene
alpha-glycosyl isoquercitrin
amino acids
anthocyanins
apricot
ascorbyl palmitate
astaxanthin
astragalus
basil
berry flavor
beta-carotene
beta-tocopherol
bilberry
black currant
black garlic
black tea
blackberry
blueberry
broccoli
Brussel sprouts
caffeine
camu camu
catalase
catechins
caterpillar mushroom
cauliflower
chokeberry
chrysin
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cryptoxanthin
turmeric
delta-tocopherol
epigallocatechin gallate (EGCG)
fish protein
flavonols
fruit blend (proprietary)
ginseng
grape
green tea
greens blend (proprietary)
guarana
hesperetin
hesperidin
HMR lignan
L-carnosine
L-cysteine
L-glutathione
L-glycine
Lentinula edodes mycelia
lutein
Matcha
Melatonin
mixed carotenoids
N-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
oyster mushroom
phenolic compounds
phospholipids
pine bark
pyrroloquinoline disodium salt
quercetin
raspberry
reishi mushroom
resveratrol
selenium
spirulina
strawberry
ubiquinol
vegetable blend (proprietary)
vitamin C
vitamin E
Whey protein
Zinc
papaya
bee pollen
lingzhi
ferulic acid
cistanche
ganoderma
royal jelly
polyphenols
fulvic acid
wheat germ
goji berry
Algae
cocoa
1,2-di-galloyl-4,6hexahydroxydiphenoyl-D-glucose
3,3'-dihydroxy-B-carotene-4,4'-dione
3-Isomangostin
5,7-Dimethoxyflavone
7,4-Dimethoxyflavone
amethoflavone
ankaflavin
apigenin
Aronia melanocarpa
Auricularia
Autumn Olive
antirrhinin
avocado
amentoflavone
Acacetin
Allophycocyanin
alpha-lipoic acid
ascorbigen
astragaloside
anthocyanidins
Algal protein
Acer truncatum
anthocyanosides
argan nut oil
apocarotenal
apocynin
arctiin
Arjunolic acid
beta-hydroxybutyrate
beta-zeacarotene
Brassica
bok choy
baccosides
BHT (butylated hydroxytoluene)
benfotiamine
Basidiomycota
betanin
berry
Brazil nut
boysenberry
BHA (butylated hydroxyanisole)
bioflavonoids
bacoside
baicalin
caffeic Acid
Camellia sinensis
Carnosine
chebulic acid
cashew
cichoric acid
chocolate
capsorubin
carnosol
cupric ascorbate
C-phycocyanin
carotene (unspecified)
chebulinic acid
crocetin
canthaxanthin
Crypthecodinium
capsanthin
carnosic acid
Dunaliella salina
dismutase
delphinidin
Dunaliella
dehydroascorbic acid
Dumontiaceae
desoxyrhaponticin
dragon fruit
dibenzo-alpha pyrones
dihydrolipoic acid
diosmetin
epicatechin
ellagic acid
ergothioneine
emblicanin
erythorbic acid
ethylgallate
eriodictyol
Ecklonia
fucoidan
flavin mononucleotide
fatty acids
furanosterols
flavanones
flavoglycosides
flavans
flavonones
flavones
Ginsenosides
Glucan peptides
Gac
gamma-glutamylcysteine
Garcinone C
Garcinone E
Glutathione
gamma-carotene
Haematococcus pluvialis
hydroxycinnamic acid
hydroxytyrosol
hydroxyphenylethanols
honeybush
isoascorbate
Idebenone
isovitexin
Jaboticaba
Kaempferol
kucha tea
Lycium
lipids
Leucodelphinidin
Methylselenocysteine
mangiferin
Mineral ascorbate
Myricitrin
macadamia
malvidin
mangostanol
mangostene xanthone
Mate
Methoxylated flavones
Neoandrographolides
Neoxanthin
N-Caffeoyldopamine
Oligomeric proanthocyanidins
Phycocyanin
pyrroloquinoline quinone
propyl gallate
Phytofluene
Phytoplankton
Plankton
polyporous mushroom
procyanidol
procyanidin
Pentacyclic triterpenoids
Phosphate ascorbate
proanthocyanidins
Phytoene
Pleurotus eryngii
Phthalides
Pentose phosphate
punicalagins
Pecan
punicosides
Pycnogenol
polymethoxylated flavones
rhammetin
Ribose-l-cysteine
rosmarinic acid
Rooibos
robusta coffee
Squalene
Salidroside
Schisandrins
Silychristin
Scopoletin
Sesamolin
Shilajit
Trigalloyl glucose
Tyrosol
Taxifolin
Tangeretin
Tiliroside
Theaflavin
Tremella
Uncaria
Vestitol
Vanillin
Withanolides
White Tea
Walnut
Xanthophyll
Xylaria nigripes
Xanthone
Yumberry

Products containing Vitamin E (mixed tocotrienols/tocopherols)

We currently have no products on Caring Sunshine that contain this ingredient.