Evidence supporting the use of: Unsaturated fatty acid
For the health condition: Free Radical Damage
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Unsaturated fatty acids, particularly polyunsaturated fatty acids (PUFAs) such as omega-3 and omega-6 fatty acids, have been studied for their roles in modulating oxidative stress and free radical damage. Scientific evidence suggests that while unsaturated fatty acids themselves are susceptible to peroxidation by free radicals, they also play important roles in supporting the body's antioxidant defense mechanisms. Some studies indicate that omega-3 PUFAs can reduce oxidative stress markers and improve antioxidant enzyme activity in humans and animals. For example, supplementation with omega-3 fatty acids has been shown to upregulate enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GPx), which help neutralize free radicals. However, the relationship is complex because unsaturated fatty acids can also become substrates for lipid peroxidation, potentially exacerbating oxidative damage if antioxidant defenses are insufficient. Therefore, their use in supporting or treating free radical damage is often recommended alongside adequate antioxidant intake from sources like vitamin E, which protects unsaturated fats from oxidation. In summary, there is moderate scientific support for the use of unsaturated fatty acids, especially omega-3s, in modulating oxidative stress, but the evidence is not unequivocal and context-dependent. Their protective effects are enhanced when combined with antioxidants, and more research is needed to clarify optimal conditions and outcomes.
More about Unsaturated fatty acid
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Other ingredients used for Free Radical Damage
7-hydroxymatairesinol (HMR)Acai berry
Acetyl L-carnitine
Alpha-carotene
alpha-glycosyl isoquercitrin
amino acids
anthocyanins
apricot
ascorbyl palmitate
astaxanthin
astragalus
basil
berry flavor
beta-carotene
beta-tocopherol
bilberry
black currant
black garlic
black tea
blackberry
blueberry
broccoli
Brussel sprouts
caffeine
camu camu
catalase
catechins
caterpillar mushroom
cauliflower
chokeberry
chrysin
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cryptoxanthin
turmeric
delta-tocopherol
epigallocatechin gallate (EGCG)
fish protein
flavonols
fruit blend (proprietary)
ginseng
grape
green tea
greens blend (proprietary)
guarana
hesperetin
hesperidin
HMR lignan
L-carnosine
L-cysteine
L-glutathione
L-glycine
Lentinula edodes mycelia
lutein
Matcha
Melatonin
mixed carotenoids
N-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
oyster mushroom
phenolic compounds
phospholipids
pine bark
pyrroloquinoline disodium salt
quercetin
raspberry
reishi mushroom
resveratrol
selenium
spirulina
strawberry
ubiquinol
vegetable blend (proprietary)
vitamin C
vitamin E
Whey protein
Zinc
papaya
bee pollen
lingzhi
ferulic acid
cistanche
ganoderma
royal jelly
polyphenols
fulvic acid
wheat germ
goji berry
Algae
cocoa
1,2-di-galloyl-4,6hexahydroxydiphenoyl-D-glucose
3,3'-dihydroxy-B-carotene-4,4'-dione
3-Isomangostin
5,7-Dimethoxyflavone
7,4-Dimethoxyflavone
amethoflavone
ankaflavin
apigenin
Aronia melanocarpa
Auricularia
Autumn Olive
antirrhinin
avocado
amentoflavone
Acacetin
Allophycocyanin
alpha-lipoic acid
ascorbigen
astragaloside
anthocyanidins
Algal protein
Acer truncatum
anthocyanosides
argan nut oil
apocarotenal
apocynin
arctiin
Arjunolic acid
beta-hydroxybutyrate
beta-zeacarotene
Brassica
bok choy
baccosides
BHT (butylated hydroxytoluene)
benfotiamine
Basidiomycota
betanin
berry
Brazil nut
boysenberry
BHA (butylated hydroxyanisole)
bioflavonoids
bacoside
baicalin
caffeic Acid
Camellia sinensis
Carnosine
chebulic acid
cashew
cichoric acid
chocolate
capsorubin
carnosol
cupric ascorbate
C-phycocyanin
carotene (unspecified)
chebulinic acid
crocetin
canthaxanthin
Crypthecodinium
capsanthin
carnosic acid
Dunaliella salina
dismutase
delphinidin
Dunaliella
dehydroascorbic acid
Dumontiaceae
desoxyrhaponticin
dragon fruit
dibenzo-alpha pyrones
dihydrolipoic acid
diosmetin
epicatechin
ellagic acid
ergothioneine
emblicanin
erythorbic acid
ethylgallate
eriodictyol
Ecklonia
fucoidan
flavin mononucleotide
fatty acids
furanosterols
flavanones
flavoglycosides
flavans
flavonones
flavones
Ginsenosides
Glucan peptides
Gac
gamma-glutamylcysteine
Garcinone C
Garcinone E
Glutathione
gamma-carotene
Haematococcus pluvialis
hydroxycinnamic acid
hydroxytyrosol
hydroxyphenylethanols
honeybush
isoascorbate
Idebenone
isovitexin
Jaboticaba
Kaempferol
kucha tea
Lycium
lipids
Leucodelphinidin
Methylselenocysteine
mangiferin
Mineral ascorbate
Myricitrin
macadamia
malvidin
mangostanol
mangostene xanthone
Mate
Methoxylated flavones
Neoandrographolides
Neoxanthin
N-Caffeoyldopamine
Oligomeric proanthocyanidins
Phycocyanin
pyrroloquinoline quinone
propyl gallate
Phytofluene
Phytoplankton
Plankton
polyporous mushroom
procyanidol
procyanidin
Pentacyclic triterpenoids
Phosphate ascorbate
proanthocyanidins
Phytoene
Pleurotus eryngii
Phthalides
Pentose phosphate
punicalagins
Pecan
punicosides
Pycnogenol
polymethoxylated flavones
rhammetin
Ribose-l-cysteine
rosmarinic acid
Rooibos
robusta coffee
Squalene
Salidroside
Schisandrins
Silychristin
Scopoletin
Sesamolin
Shilajit
Trigalloyl glucose
Tyrosol
Taxifolin
Tangeretin
Tiliroside
Theaflavin
Tremella
Uncaria
Vestitol
Vanillin
Withanolides
White Tea
Walnut
Xanthophyll
Xylaria nigripes
Xanthone
Yumberry
Other health conditions supported by Unsaturated fatty acid
Alzheimer's DiseaseAngina
Arteriosclerosis
Arthritis
Asthma
Blood Clots (prevention of)
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Congestive Heart Failure
Depression
Diabetes
Fatty Liver Disease
Free Radical Damage
Heart (weakness)
Heart Fibrillation or Palpitations
Hypertension
Inflammation
Inflammatory Bowel Disorders
Memory and Brain Function
Metabolic Syndrome
Migraine
Multiple Sclerosis
Osteoporosis
Parkinson's Disease
Peripheral Neuropathy
Psoriasis
Rheumatoid Arthritis
Stress
Strokes
Triglycerides (high)
Wounds and Sores