Rosemary antioxidant S-32 is a standardized extract derived from the rosemary plant (Rosmarinus officinalis), primarily containing compounds such as carnosic acid and carnosol. These constituents are well-documented for their antioxidant properties in scientific literature. Numerous in vitro and animal studies have demonstrated that rosemary extract and its active molecules can neutralize free radicals, reduce lipid peroxidation, and enhance endogenous antioxidant defenses. For example, carnosic acid has been shown to directly scavenge reactive oxygen species (ROS) and upregulate antioxidant enzymes like superoxide dismutase (SOD) and catalase. Rosemary extracts are also used as natural preservatives in the food industry due to their ability to prevent oxidative spoilage.

While most evidence comes from laboratory and preclinical studies, limited human clinical trials suggest that rosemary extract supplementation can increase antioxidant status and reduce markers of oxidative stress. However, the clinical relevance and optimal dosing for treating or preventing free radical damage in humans is not yet fully established. Regulatory bodies such as the European Food Safety Authority (EFSA) recognize rosemary extracts as safe for use in food, but specific health claims regarding free radical damage are not universally approved. Overall, the use of rosemary antioxidant S-32 for supporting free radical damage is grounded in scientific evidence, especially at the mechanistic and preclinical levels, but more robust human data are needed for definitive clinical recommendations.