Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Coenzyme Q10 (CoQ10) is justified by scientific validation for use in supporting or treating free radical damage. CoQ10 is a lipid-soluble antioxidant naturally present in the mitochondria of cells, where it plays a crucial role in the electron transport chain and energy production. Its antioxidant properties allow it to neutralize free radicals and reduce oxidative stress, which is a key contributor to cellular damage and aging. Several in vitro and animal studies have demonstrated that CoQ10 supplementation can decrease markers of oxidative damage in tissues. In humans, clinical studies have shown that CoQ10 supplementation can increase antioxidant capacity in plasma and reduce biomarkers of oxidative stress, particularly in populations with increased oxidative burden, such as individuals with cardiovascular disease, diabetes, and neurodegenerative disorders.

However, while the biochemical basis and preclinical data are robust, clinical trials in healthy populations or for general prevention of oxidative damage are less conclusive, and the translation to broad therapeutic recommendations is still debated. The evidence is strongest for specific conditions associated with increased oxidative stress, but more research is needed to fully establish its efficacy for general free radical damage in otherwise healthy individuals. Overall, current data support a moderate scientific basis (rated 3 out of 5) for the use of CoQ10 in managing free radical damage, particularly in clinical contexts with elevated oxidative stress.

More about coenzyme Q10 (CoQ10)
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Other ingredients used for Free Radical Damage

Other health conditions supported by coenzyme Q10 (CoQ10)

Products containing coenzyme Q10 (CoQ10)

Nature's Sunshine Cellular Energy
Nature's Sunshine Circulatory System
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Nature's Sunshine SnorEase