Chaga mushroom (Inonotus obliquus) has been traditionally used in folk medicine, particularly in Russia and parts of Asia, but its use to support or treat free radical damage is supported by some modern scientific studies. Research has identified that Chaga contains high levels of polyphenols, melanin, and triterpenoids—compounds known for their antioxidant properties. In vitro (test tube) studies have shown that Chaga extracts can scavenge free radicals and reduce oxidative stress, which is the primary mechanism of free radical damage at the cellular level (Zhao et al., 2013). Animal studies also suggest that Chaga supplementation may increase antioxidant enzyme activity and reduce markers of oxidative stress.

However, there is a lack of robust clinical trials in humans to confirm these effects. Most of the evidence comes from laboratory and animal research, which does not always translate to clear benefits in humans. Therefore, while the antioxidant potential of Chaga is scientifically plausible and supported by preliminary studies, the evidence remains limited, and more high-quality human research is needed to establish efficacy and appropriate dosing for mitigating free radical damage.