Evidence supporting the use of: Vitamin B9 (Calcium Folinate)
For the body system: Female Reproductive System
Synopsis
Source of validity: Scientific
Rating (out of 5): 5
Calcium folinate (also known as folinic acid) is a form of Vitamin B9 and is scientifically validated in its role supporting the female reproductive system, especially in the context of pregnancy and fertility. Folate is essential for DNA synthesis, repair, and methylation, processes critical for cell division and growth. Adequate folate intake before and during pregnancy is well-established to reduce the risk of neural tube defects (NTDs) such as spina bifida in the developing fetus. Numerous clinical guidelines, including those from the US Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), recommend folate supplementation for women of reproductive age, particularly those planning pregnancy.
Calcium folinate is sometimes used specifically when standard folic acid may not be metabolized efficiently (e.g., in women with MTHFR gene mutations). Folinic acid bypasses some of the metabolic steps required by folic acid, ensuring adequate tissue folate levels. Scientific studies have shown that folinic acid supplementation can also support fertility treatments and improve pregnancy outcomes in certain populations. Overall, the use of Vitamin B9 (folate/folinic acid) for supporting the female reproductive system is strongly backed by scientific evidence, particularly for its role in fetal neural development and prevention of birth defects.
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Other body systems supported by Vitamin B9 (Calcium Folinate)
BloodBrain
Female Reproductive System
Reproductive System