Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B complex, which includes several B vitamins (such as B6, B9/folate, and B12), has scientific support for its role in supporting the female reproductive system. The B vitamins are crucial for energy metabolism, hormone regulation, and cellular function. Folate (vitamin B9) is particularly essential for women of reproductive age, as it plays a key role in DNA synthesis and cell division, which are vital for fetal development during pregnancy. Adequate folate intake before and during early pregnancy significantly reduces the risk of neural tube defects in newborns, a relationship supported by extensive clinical and epidemiological research. Vitamin B6 is involved in the regulation of homocysteine, neurotransmitter synthesis, and hormone balance; studies have shown it can alleviate symptoms of premenstrual syndrome (PMS) and support reproductive hormone function. Vitamin B12 works closely with folate in DNA synthesis and red blood cell formation, and deficiencies in B12 can contribute to infertility and complications during pregnancy. Overall, the scientific evidence justifies the use of B vitamins, particularly folate, B6, and B12, in supporting female reproductive health, fertility, pregnancy outcomes, and menstrual health. However, the evidence is strongest for folate, and less robust but still significant for B6 and B12, resulting in a high but not perfect evidence score.

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