Evidence supporting the use of: Linoleic acid (LA)
For the body system: Female Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Linoleic acid (LA) is an essential omega-6 polyunsaturated fatty acid found in many vegetable oils, nuts, and seeds. Its role in the female reproductive system has some scientific basis, though evidence is moderate. LA is a precursor for important bioactive lipids, such as prostaglandins, which are involved in the regulation of the menstrual cycle, ovulation, and uterine function. Some studies have suggested that a balanced intake of omega-6 and omega-3 fatty acids may positively affect reproductive health, possibly by supporting normal hormonal function and reducing inflammation that can impact fertility.

However, the evidence is not robust. Most human studies focus on overall dietary patterns rather than isolated supplementation of linoleic acid. Some animal studies indicate that both deficiencies and excessive intakes of LA can negatively impact ovarian function and fertility. Additionally, epidemiological data suggest that essential fatty acids, including LA, are necessary for normal menstrual function and fetal development during pregnancy.

Despite these findings, there is limited direct clinical trial evidence demonstrating that supplemental linoleic acid alone improves any specific aspect of female reproductive health. The current scientific consensus supports adequate intake of LA as part of a balanced diet, rather than high-dose supplementation specifically for reproductive purposes. Thus, while there is some scientific rationale for its role in reproductive health, the evidence for targeted supplementation is limited.

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Other ingredients that support Female Reproductive System

25-d-spirosta-3, 5-diene
27-deoxyactein
7-hydroxymatairesinol (HMR)
8-Prenylnaringenin
Abuta
Agnuside
AHCC
Alchemilla
Aletris
amino acids
anamu
anemarrhena asphodeloides
Anemone
Angelica
animal protein
anise
Anserina
Ashoka
ashwagandha
barbasco
basil
Belamcanda
bethroot
betony
bird\'s nest
black cohosh
blessed thistle
blue cohosh
borage oil
broccoli
bugbane
Caesalpinia crista
Calochortus
casticin
Ceylon leadwort
chaste tree
Chinese pond turtle
Chlorophytum
Clary sage
Cnidium
cohosh
cramp bark
Crinum latifolium
Cynomorium
d-alpha tocopherol
daidzein
damiana
dandelion
date
DHEA
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dioscorea
diosgenin
dodder
dong quai
dong quai root
egg
eleuthero
equol (proprietary)
Erythrina
estrogen
evening primrose oil
evening primrose oil
false unicorn root
fatty acids
fennel
fenugreek
flaxseed
fo-ti
folate
folic acid
formononetin
furostanols
gamma linolenic acid (GLA)
genistein
giant trillium
ginger
Ginsenosides
goat\'s rue
golden ragwort
goldenseal
guelder rose
herbal blend (proprietary)
hibiscus
HMR lignan
horny goat weed
Hypericum
Indian fagonia
Indian tinospora
indole-3-carbinol
inositol
inositol phosphate
isoflavones
jasmine
jujube
Kigelia africana
Labisia pumila
labrador tea
Lactobacillus acidophilus
Lactobacillus crispatus
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus jensenii
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus salivarius
Lady's Mantle
Laminaria
Leptadenia
lignans
ligustilides
lingzhi
linoleic acid (LA)
lipids
Loranthus
maca
macaenes
macamides
mandrake
Marine lipid
Miroestrol
Montanoa tomentosa
Motherwort
Mugwort
Nettle
Nigella seed
omega-3 fatty acids
Pennyroyal
peony
Phytoestrogens
polyunsaturated fat
Puerain
Pulsatilla
raspberry
red clover
rose
rose oil
royal jelly
Rubia cordifolia
Rubus
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Safed musli
saffron
selenium
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shepherd's purse
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soybean
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spearmint leaf
squawvine
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tribulus
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Vitex Agnus-Castus
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Products containing linoleic acid (LA)

Nature's Sunshine Evening Primrose Oil