Evidence supporting the use of: Linoleic acid (LA)
For the body system: Female Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Linoleic acid (LA) is an essential omega-6 polyunsaturated fatty acid found in many vegetable oils, nuts, and seeds. Its role in the female reproductive system has some scientific basis, though evidence is moderate. LA is a precursor for important bioactive lipids, such as prostaglandins, which are involved in the regulation of the menstrual cycle, ovulation, and uterine function. Some studies have suggested that a balanced intake of omega-6 and omega-3 fatty acids may positively affect reproductive health, possibly by supporting normal hormonal function and reducing inflammation that can impact fertility.

However, the evidence is not robust. Most human studies focus on overall dietary patterns rather than isolated supplementation of linoleic acid. Some animal studies indicate that both deficiencies and excessive intakes of LA can negatively impact ovarian function and fertility. Additionally, epidemiological data suggest that essential fatty acids, including LA, are necessary for normal menstrual function and fetal development during pregnancy.

Despite these findings, there is limited direct clinical trial evidence demonstrating that supplemental linoleic acid alone improves any specific aspect of female reproductive health. The current scientific consensus supports adequate intake of LA as part of a balanced diet, rather than high-dose supplementation specifically for reproductive purposes. Thus, while there is some scientific rationale for its role in reproductive health, the evidence for targeted supplementation is limited.

More about linoleic acid (LA)
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Other ingredients that support Female Reproductive System

7-hydroxymatairesinol (HMR)
amino acids
ashwagandha
basil
black cohosh
borage oil
broccoli
chaste tree
turmeric
d-alpha tocopherol
damiana
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
eleuthero
evening primrose oil
fennel
fenugreek
flaxseed
folate
gamma linolenic acid (GLA)
genistein
ginger
goldenseal
hibiscus
HMR lignan
Indian tinospora
indole-3-carbinol
inositol
jujube
lactobacillus acidophilus
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus jensenii
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lignans
linoleic acid (LA)
maca
marine lipid
motherwort
nettle
omega-3 fatty acids
raspberry
rose oil
saffron
selenium
soybean
spearmint leaf
tribulus
vitamin B
vitamin B6
vitamin E
wild yam
red clover
squawvine
mugwort
anise
caesalpinia crista
rubia cordifolia
blessed thistle
peony
lingzhi
lingusticum wallichii
yarrow
yarrow
dioscorea
dodder
royal jelly
Equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
shepherd's purse
wood betony
herbal blend (proprietary)
soy isoflavones
27-deoxyactein
25-d-spirosta-3, 5-diene
8-Prenylnaringenin
Angelica
Anamu
AHCC
Alchemilla
Aletris
Anserina
Anemone
Agnuside
Ashoka
Abuta
Animal protein
Betony
Blue Cohosh
Bugbane
Bethroot
Barbasco
Belamcanda
Bird's nest
Calochortus
Cohosh
Clary sage
Cnidium
Cynomorium
Cramp Bark
Chinese Pond Turtle
Chlorophytum
Casticin
Ceylon Leadwort
Crinum latifolium
DHEA
Daidzein
Dong Quai
Diosgenin
Date
Egg
Erythrina
Evening Primrose
Estrogen
Isoflavones
jasmine
Pennyroyal
Rose
Soy Protein
Vervain

Products containing linoleic acid (LA)

Nature's Sunshine Evening Primrose Oil