Evidence supporting the use of: Goldenseal
For the body system: Female Reproductive System

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Goldenseal (Hydrastis canadensis) has a long history of use in traditional herbal medicine, particularly among Native American tribes and later in Western herbal traditions. It has primarily been used as a remedy for infections, inflammation, and digestive issues. Historically, some herbalists included goldenseal in formulas for women’s reproductive health, mainly for its purported antimicrobial and anti-inflammatory effects. For example, it was sometimes used as a wash or douche for vaginal infections or to address irregular menstrual cycles, though these uses were based on empirical tradition rather than controlled studies.

However, there is very limited scientific evidence supporting goldenseal’s efficacy specifically for the female reproductive system. Most modern research focuses on its general antimicrobial properties due to its active compounds, such as berberine, rather than on direct benefits to reproductive health. There are no robust clinical trials demonstrating benefits for menstrual health, hormonal balance, or other aspects of the female reproductive system. Furthermore, goldenseal is not considered a mainstream herb for reproductive health in contemporary herbalism, and its use for this purpose is far less common today. In summary, goldenseal’s association with female reproductive system support is rooted in tradition rather than scientific validation, and the evidence base is weak.

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inositol
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