Evidence supporting the use of: Evening primrose oil
For the body system: Female Reproductive System
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Evening primrose oil (EPO) has a long history of traditional use for supporting the female reproductive system, particularly for conditions such as premenstrual syndrome (PMS), breast pain (mastalgia), and menopausal symptoms. The oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid thought to influence prostaglandin production and, therefore, hormone regulation and inflammation. Many women have historically used EPO as a natural remedy to alleviate symptoms like breast tenderness, mood swings, and menstrual cramps.
However, when examining the scientific evidence, support for these uses is limited and inconsistent. Reviews of clinical trials have found that EPO is no more effective than placebo for PMS or mastalgia in most well-conducted studies. Multiple systematic reviews, including Cochrane analyses, generally conclude there is little reliable evidence to recommend EPO for these reproductive health concerns. Some small studies have suggested minor benefits, but these are often offset by methodological flaws, small sample sizes, or lack of replication.
As such, evening primrose oil’s reputation for supporting the female reproductive system rests largely on tradition and anecdotal reports rather than robust scientific validation. While it is widely used for this purpose, consumers should be aware that current scientific research does not strongly support its effectiveness for reproductive or hormonal health issues.
More about evening primrose oil
More about Female Reproductive System
Other ingredients that support Female Reproductive System
25-d-spirosta-3, 5-diene27-deoxyactein
7-hydroxymatairesinol (HMR)
8-Prenylnaringenin
Abuta
Agnuside
AHCC
Alchemilla
Aletris
amino acids
anamu
anemarrhena asphodeloides
Anemone
Angelica
animal protein
anise
Anserina
Ashoka
ashwagandha
barbasco
basil
Belamcanda
bethroot
betony
bird\'s nest
black cohosh
blessed thistle
blue cohosh
borage oil
broccoli
bugbane
Caesalpinia crista
Calochortus
casticin
Ceylon leadwort
chaste tree
Chinese pond turtle
Chlorophytum
Clary sage
Cnidium
cohosh
cramp bark
Crinum latifolium
Cynomorium
d-alpha tocopherol
daidzein
damiana
dandelion
date
DHEA
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dioscorea
diosgenin
dodder
dong quai
dong quai root
egg
eleuthero
equol (proprietary)
Erythrina
estrogen
evening primrose oil
evening primrose oil
false unicorn root
fatty acids
fennel
fenugreek
flaxseed
fo-ti
folate
folic acid
formononetin
furostanols
gamma linolenic acid (GLA)
genistein
giant trillium
ginger
Ginsenosides
goat\'s rue
golden ragwort
goldenseal
guelder rose
herbal blend (proprietary)
hibiscus
HMR lignan
horny goat weed
Hypericum
Indian fagonia
Indian tinospora
indole-3-carbinol
inositol
inositol phosphate
isoflavones
jasmine
jujube
Kigelia africana
Labisia pumila
labrador tea
Lactobacillus acidophilus
Lactobacillus crispatus
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus jensenii
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus salivarius
Lady's Mantle
Laminaria
Leptadenia
lignans
ligustilides
lingzhi
linoleic acid (LA)
lipids
Loranthus
maca
macaenes
macamides
mandrake
Marine lipid
Miroestrol
Montanoa tomentosa
Motherwort
Mugwort
Nettle
Nigella seed
omega-3 fatty acids
Pennyroyal
peony
Phytoestrogens
polyunsaturated fat
Puerain
Pulsatilla
raspberry
red clover
rose
rose oil
royal jelly
Rubia cordifolia
Rubus
rue
Safed musli
saffron
selenium
Shataverins
shepherd's purse
Sichuan Lovage
Soy
soy isoflavones
Soy Protein
soybean
Sparganium
spearmint leaf
squawvine
Szechuan lovage
Taxillus chinensis
trace minerals
tribulus
turmeric
Vervain
Viburnum
vitamin B
vitamin B6
vitamin E
Vitex Agnus-Castus
Vitexicarpin
White Dead Nettle Flower
Wild yam
Wood betony
Yarrow
Yarrow
Other body systems supported by evening primrose oil
BreastsFemale Reproductive System
Joints
Ovaries
Prostaglandins
Reproductive System
Skin
Vagina
Products containing evening primrose oil
Nature's Sunshine Evening Primrose Oil
Nature's Sunshine Natural Changes
Nature's Sunshine Super GLA
