Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Dodder (Cuscuta spp.) has been used in traditional medicine systems, particularly in Traditional Chinese Medicine (TCM), to support aspects of female reproductive health. In TCM, dodder seed (called “Tu Si Zi”) is believed to tonify the kidney and liver, strengthen the yang, and stabilize essence—concepts that are historically linked to fertility and reproductive function in women. Traditional uses include addressing conditions such as infertility, habitual miscarriage, and irregular menstruation. The herb is often included in multi-herb formulas intended to enhance reproductive health or to “nourish the womb.” However, while there are some animal studies suggesting dodder seed extracts may influence hormone regulation or ovarian function, robust clinical evidence in humans is lacking. No high-quality randomized controlled trials have confirmed its effectiveness for female reproductive issues. Therefore, its use is primarily justified by longstanding traditional practices rather than scientific validation. The evidence score reflects the presence of historical use and limited preclinical data, but the absence of strong clinical proof.

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