Synopsis

Source of validity: Scientific
Rating (out of 5): 3

DHEA (dehydroepiandrosterone) is a steroid hormone produced primarily by the adrenal glands, and it serves as a precursor to both androgens and estrogens. Its use in supporting the female reproductive system, particularly in the context of fertility and ovarian function, has some scientific basis. Several clinical studies have investigated DHEA supplementation as an adjunct in women with diminished ovarian reserve or those undergoing in vitro fertilization (IVF). Some research suggests that DHEA may improve ovarian response, increase the number of retrieved oocytes, and potentially improve pregnancy rates in women with poor ovarian reserve. However, the quality of evidence is moderate, with some studies showing benefits and others showing minimal or no effect. The mechanism is thought to involve DHEA's role as a precursor to sex hormones, potentially enhancing ovarian follicle development. Major reproductive medicine societies generally suggest that evidence is not yet strong enough for routine use, but DHEA may be considered in selected cases under medical supervision. DHEA is not a traditional herbal remedy for female reproductive health; its use is based on recent clinical research and understanding of endocrine physiology. More large-scale, randomized controlled trials are needed to confirm efficacy and establish safety for this indication.

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