Evidence supporting the use of: Spirulina
For the health condition: Fatty Liver Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Spirulina, a blue-green algae, has attracted scientific attention for its potential benefits in supporting liver health, including in the context of Fatty Liver Disease (NAFLD). Preclinical studies and a limited number of small clinical trials have investigated its effects on liver function and lipid metabolism. Spirulina is rich in antioxidants, particularly phycocyanin, and contains essential amino acids, vitamins, and minerals that may exert hepatoprotective effects. Animal studies suggest that spirulina supplementation can reduce liver fat accumulation, inflammation, and oxidative stress—key factors involved in the progression of fatty liver disease. These effects are likely due to spirulina’s modulation of lipid metabolism and its antioxidant activity.

Human evidence, while promising, remains limited. A few small-scale randomized controlled trials have reported improvements in liver enzyme levels (such as ALT and AST) and lipid profiles in NAFLD patients who consumed spirulina supplements. However, these studies often have methodological limitations, including small sample sizes and short durations. There are currently no large-scale, long-term clinical trials confirming spirulina's effectiveness as a treatment for fatty liver disease.

In summary, while traditional use for liver disorders is minimal, the modern scientific rationale for spirulina’s use in fatty liver disease is grounded in emerging but still preliminary evidence. Further robust clinical research is required before spirulina can be recommended as a standard therapy for NAFLD.

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alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
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artichoke
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astaxanthin
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avocado
baicalein
baicalin
banaba
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berberine
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betanin
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corilagin
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