Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Epigallocatechin gallate (EGCG), the primary catechin in green tea, has been studied for its potential effects on fat metabolism. Several clinical and preclinical studies provide moderate scientific evidence that EGCG may support fat oxidation and improve metabolic parameters related to lipid metabolism. Mechanistically, EGCG appears to enhance thermogenesis and fat oxidation, partly by inhibiting the enzyme catechol-O-methyltransferase (COMT), which degrades norepinephrine, thus prolonging sympathetic nervous system activity and increasing energy expenditure. Additionally, EGCG may modulate the expression of genes involved in lipid metabolism (such as upregulating fatty acid oxidation enzymes and downregulating lipogenic genes).

Randomized controlled trials have shown that green tea extracts rich in EGCG can lead to modest reductions in body fat, particularly when combined with caffeine. For example, a meta-analysis published in Obesity Reviews (2011) found that green tea catechins led to statistically significant, albeit modest, reductions in body weight and fat mass. However, the effects are generally small and may not be clinically significant for all individuals. The magnitude of these effects appears to vary with dosage, duration, and the presence of caffeine.

In summary, there is scientific support (though not overwhelmingly strong) that EGCG can aid fat metabolism, primarily by increasing fat oxidation and thermogenesis. While the evidence is not robust enough to recommend EGCG as a stand-alone treatment for poor fat metabolism, it may offer supportive benefits as part of a broader lifestyle approach to metabolic health.

More about epigallocatechin gallate (EGCG)
More about Fat Metabolism (poor)

Other ingredients used for Fat Metabolism (poor)

Other health conditions supported by epigallocatechin gallate (EGCG)

Products containing epigallocatechin gallate (EGCG)