Evidence supporting the use of: Capsaicinoids
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Capsaicinoids, the active compounds found in chili peppers, have garnered scientific interest for their potential role in supporting fat metabolism and weight management. Several clinical studies and meta-analyses suggest that capsaicinoids may slightly increase energy expenditure and fat oxidation in humans. The primary mechanism appears to be the activation of the transient receptor potential vanilloid 1 (TRPV1) receptor, which can increase thermogenesis (heat production) and stimulate the sympathetic nervous system, leading to elevated metabolic rate and fat oxidation.
Randomized controlled trials have demonstrated that capsaicinoid supplementation can lead to modest increases in daily energy expenditure (by about 50 kcal/day) and may enhance fat oxidation, particularly when combined with other lifestyle interventions like calorie restriction or exercise. Some research also shows that capsaicinoids may reduce appetite and caloric intake, contributing indirectly to weight management.
However, the clinical effects are generally modest, and long-term impacts on body weight and fat mass are less well established. The safety profile of capsaicinoids is favorable for most individuals, but gastrointestinal side effects may occur at higher doses. In summary, while capsaicinoids are not a standalone solution for poor fat metabolism, there is moderate scientific evidence supporting their adjunctive use in promoting fat oxidation and supporting metabolic health.
Other ingredients used for Fat Metabolism (poor)
3-desoxy-7-KETO-DHEA7-Keto-DHEA
Acetyl L-carnitine
Alpha methyl tetradecylthioacetic acid
alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
anchovies
apple cider vinegar
artichoke
avocado
barberry
Berberis (unspecified)
beta-hydroxybutyrate
bile salt
biotin
black ginger
capric acid
capsaicin
capsaicinoids
capsiate
capsinoids
cardarine
carqueja
cha de bugre
chia seed
choline
cinnamon
coconut oil
Coleus forskohlii
conjugated linoleic acid (CLA)
coriander
dandelion
diacylglycerol
dihydrocapsiate
ephedrine
epigallocatechin gallate (EGCG)
evodiamine
fenugreek
flavanones
flavonols
forskohlii root
forskolin
fucoxanthin
garcinia
ginger
glucomannan
grains of paradise
guggul
gymnemic acids
hesperetin
Higenamine
hydroxycitric acid
isomaltulose
kelp
l-carnitine
lecithin
Legume protein
linoleic acid (LA)
lipase
lipstatin
macadamia
medium chain triglycerides (MCT)
Milk thistle
Monounsaturated fat
Oleoylethanolamide
omega-3 fatty acids
omega-7 fatty acids
oolong tea
Palatinose
palmitate
pantethine
Perperine
phaseolamin
phospholipids
Pinolenic acid
polyphenols
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
turmeric
Ursolic Acid
vitamin B
Wakame
Walnut
Yohimbine
Zinc
Other health conditions supported by capsaicinoids
Peripheral NeuropathyArthritis
Athletic and Exercise Aids
Backache
Body Building
Bronchitis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Circulation (poor)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Diabetes
Digestion (poor)
Energy (lack of)
Exercise
Fat Metabolism (poor)
