Evidence supporting the use of: Capsaicinoids
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Capsaicinoids, the active compounds found in chili peppers, have garnered scientific interest for their potential role in supporting fat metabolism and weight management. Several clinical studies and meta-analyses suggest that capsaicinoids may slightly increase energy expenditure and fat oxidation in humans. The primary mechanism appears to be the activation of the transient receptor potential vanilloid 1 (TRPV1) receptor, which can increase thermogenesis (heat production) and stimulate the sympathetic nervous system, leading to elevated metabolic rate and fat oxidation.
Randomized controlled trials have demonstrated that capsaicinoid supplementation can lead to modest increases in daily energy expenditure (by about 50 kcal/day) and may enhance fat oxidation, particularly when combined with other lifestyle interventions like calorie restriction or exercise. Some research also shows that capsaicinoids may reduce appetite and caloric intake, contributing indirectly to weight management.
However, the clinical effects are generally modest, and long-term impacts on body weight and fat mass are less well established. The safety profile of capsaicinoids is favorable for most individuals, but gastrointestinal side effects may occur at higher doses. In summary, while capsaicinoids are not a standalone solution for poor fat metabolism, there is moderate scientific evidence supporting their adjunctive use in promoting fat oxidation and supporting metabolic health.
Other ingredients used for Fat Metabolism (poor)
7-Keto-DHEAacetyl l-carnitine
alpha-linolenic acid (ALA)
anchovies
artichoke
barberry
biotin
canola oil
capsaicinoids
choline
cinnamon
coleus forskohlii
conjugated linoleic acid (CLA)
turmeric
dandelion
epigallocatechin gallate (EGCG)
fenugreek
flavonols
forskohlii root
garcinia
ginger
glucomannan
guggul
hesperetin
hydroxycitric acid
kelp
l-carnitine
lecithin
linoleic acid (LA)
lipase
medium chain triglycerides (MCT)
milk thistle
omega-3 fatty acids
omega-7 fatty acids
palmitate
pantethine
phospholipids
black ginger
vitamin B
zinc
bile salt
polyphenols
AMP-activated protein kinase (AMPK)
3-desoxy-7-KETO-DHEA
Apple Cider Vinegar
Avocado
alpha Methyl Tetradecylthioacetic Acid
Beta-hydroxybutyrate
Berberis (unspecified)
Chia seed
Capric Acid
Cardarine
Carqueja
Capsinoids
coconut oil
Coriander
Capsaicin
Capsiate
Cha de bugre
Diacylglycerol
Dihydrocapsiate
Ephedrine
walnut
yohimbine
Other health conditions supported by capsaicinoids
ArthritisAthletic and Exercise Aids
Backache
Body Building
Bronchitis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Circulation (poor)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Diabetes
Digestion (poor)
Energy (lack of)
Exercise
Fat Metabolism (poor)
Peripheral Neuropathy