Evidence supporting the use of: Artichoke
For the health condition: Fat Metabolism (poor)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Artichoke (Cynara scolymus) has been traditionally used to support liver and digestive health, but recent scientific research has begun to elucidate its role in fat metabolism. Several clinical studies and reviews suggest that artichoke leaf extract can have a modest effect on lipid metabolism and liver function, which are closely related to the body's handling of fats. The active compounds in artichoke, such as cynarin and chlorogenic acid, are believed to stimulate bile production, which aids in the digestion and absorption of dietary fats. Some randomized controlled trials have demonstrated that artichoke extracts may help reduce total cholesterol, LDL cholesterol, and triglyceride levels in patients with mild hyperlipidemia, indicating an improvement in fat metabolism. A 2017 systematic review published in Phytomedicine found a small but significant cholesterol-lowering effect of artichoke leaf extract compared to placebo. Additionally, animal studies have shown enhanced liver antioxidant capacity and improved lipid profiles following artichoke supplementation. However, while these findings are promising, the overall quality and quantity of clinical evidence remain moderate, and larger, well-designed studies are needed to confirm these effects and determine optimal dosing. In summary, there is a moderate level of scientific evidence supporting the use of artichoke for improving aspects of fat metabolism, particularly in relation to cholesterol management and liver function, but more robust research is needed for definitive conclusions.
Other ingredients used for Fat Metabolism (poor)
7-Keto-DHEAacetyl l-carnitine
alpha-linolenic acid (ALA)
anchovies
artichoke
barberry
biotin
canola oil
capsaicinoids
choline
cinnamon
coleus forskohlii
conjugated linoleic acid (CLA)
turmeric
dandelion
epigallocatechin gallate (EGCG)
fenugreek
flavonols
forskohlii root
garcinia
ginger
glucomannan
guggul
hesperetin
hydroxycitric acid
kelp
l-carnitine
lecithin
linoleic acid (LA)
lipase
medium chain triglycerides (MCT)
milk thistle
omega-3 fatty acids
omega-7 fatty acids
palmitate
pantethine
phospholipids
black ginger
vitamin B
zinc
bile salt
polyphenols
AMP-activated protein kinase (AMPK)
3-desoxy-7-KETO-DHEA
Apple Cider Vinegar
Avocado
alpha Methyl Tetradecylthioacetic Acid
Beta-hydroxybutyrate
Berberis (unspecified)
Chia seed
Capric Acid
Cardarine
Carqueja
Capsinoids
coconut oil
Coriander
Capsaicin
Capsiate
Cha de bugre
Diacylglycerol
Dihydrocapsiate
Ephedrine
walnut
yohimbine
Other health conditions supported by artichoke
Abdominal PainAcid Indigestion
Cholesterol (high)
Cirrhosis of the Liver
Dyspepsia
Fat Metabolism (poor)
Fatty Liver Disease
Gall Bladder (sluggish or removed)
Gall Stones
Gas and Bloating
Gastritis
Indigestion
Jaundice (adults)
Liver Detoxification
Triglycerides (high)