Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Orange pigments, particularly carotenoids such as beta-carotene, lutein, and zeaxanthin, are widely studied for their role in supporting eye health and vision. These compounds are found in high concentrations in orange-colored fruits and vegetables like carrots, sweet potatoes, and pumpkins. Beta-carotene is a precursor to vitamin A, which is essential for the maintenance of normal vision. A deficiency in vitamin A can lead to night blindness and, in severe cases, complete blindness. Lutein and zeaxanthin, also orange-yellow pigments found in foods such as corn and orange bell peppers, are present in the macula of the human retina and are believed to protect the eyes by absorbing harmful blue light and acting as antioxidants.

Numerous epidemiological and clinical studies support the role of these pigments in reducing the risk of age-related macular degeneration (AMD) and cataracts. For example, the Age-Related Eye Disease Study (AREDS2) demonstrated that supplementation with lutein and zeaxanthin reduced the risk of progression to advanced AMD. While the evidence for beta-carotene is strong for preventing vitamin A deficiency-related vision problems, there is less support for its use in preventing other eye diseases, especially in well-nourished populations. Overall, there is substantial scientific validation for the use of orange pigments, especially lutein and zeaxanthin, in supporting eyesight and preventing certain age-related eye conditions.

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