Evidence supporting the use of: Lutein
For the health condition: Eyesight (poor)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lutein is a carotenoid found naturally in high concentrations in the macula of the human retina. Its primary role is thought to be the filtration of high-energy blue light and acting as an antioxidant to protect retinal tissues from oxidative stress. Scientific studies, including large randomized controlled trials such as the Age-Related Eye Disease Study 2 (AREDS2), have investigated lutein supplementation for the prevention and management of age-related macular degeneration (AMD), a major cause of poor eyesight in older adults. Results from AREDS2 and subsequent meta-analyses suggest that lutein, often in combination with zeaxanthin, may modestly reduce the risk of progression to advanced AMD in individuals at high risk. However, evidence for lutein's effectiveness in improving general eyesight or preventing other types of poor vision (such as myopia or cataracts) is less robust. While the evidence supports a role for lutein in eye health, particularly regarding AMD, the effect size appears moderate, and lutein is not a cure but rather a supportive measure. Dietary intake of lutein through green leafy vegetables and supplementation is generally considered safe. In summary, scientific evidence justifies the use of lutein as a supportive intervention for certain eye conditions associated with poor eyesight, especially AMD, but it is not a panacea for all vision problems.

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