Evidence supporting the use of: Anthocyanidins
For the health condition: Eyesight (poor)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Anthocyanidins, a class of flavonoids found in various fruits and vegetables (notably in berries, grapes, and purple corn), have been investigated for their potential benefits in supporting eye health. Scientific interest in anthocyanidins for eyesight stems from their antioxidant and anti-inflammatory properties, which are hypothesized to protect ocular tissues from oxidative stress—a contributor to age-related vision decline and retinal damage.

Several laboratory and small-scale clinical studies suggest that anthocyanidins, particularly those found in bilberry (Vaccinium myrtillus), may improve certain aspects of visual function. For example, limited trials have indicated improvements in night vision and faster adaptation to darkness in healthy subjects. Some studies also report potential protective effects against diabetic retinopathy and macular degeneration due to anthocyanidins' ability to strengthen capillaries and reduce retinal inflammation.

However, the overall quality of evidence is modest. Most human studies are small, short-term, or lack rigorous controls, and meta-analyses indicate that while there is a biochemical rationale and some positive findings, conclusive evidence for substantial clinical benefit is lacking. Thus, while anthocyanidins are widely promoted for eye health and have a plausible mechanism of action, their use for improving poor eyesight is supported by only limited scientific evidence at this time.

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