Evidence supporting the use of: Goldenseal
For the health condition: Eyes (red or itching)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Goldenseal (Hydrastis canadensis) has a long history of use in traditional herbal medicine, particularly among Native American tribes and later in Western herbalism. It was commonly used as a topical wash or eyewash for red, irritated, or infected eyes, sometimes in combination with other botanicals like boric acid. The plant contains alkaloids such as berberine, hydrastine, and canadine, which have antimicrobial properties. This traditional use was based on the belief that goldenseal could help reduce inflammation and fight infection when applied to the eyes.

However, modern scientific research validating goldenseal's effectiveness or safety for eye conditions is extremely limited. While berberine (a key constituent) does have documented antimicrobial activity in vitro, there is a lack of robust clinical trials or ophthalmological studies supporting the use of goldenseal or its extracts for treating conjunctivitis, red eyes, or other ocular inflammation in humans. Furthermore, ophthalmologists typically do not recommend goldenseal for eye problems due to potential irritation, lack of dosing standards, and risk of contamination. In summary, the use of goldenseal for red or itching eyes is primarily justified by tradition, not by scientific evidence, and should be approached with caution.

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