Evidence supporting the use of: Vitamin E (alpha tocopheryl)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E (specifically alpha-tocopherol) is an antioxidant that has been studied for its potential role in supporting eye health, particularly in relation to age-related macular degeneration (AMD) and cataracts. The scientific interest in Vitamin E for eye health stems from its ability to neutralize free radicals, which are implicated in oxidative damage to retinal cells—a process believed to contribute to common degenerative eye conditions.

The most notable clinical trial in this area is the Age-Related Eye Disease Study (AREDS and AREDS2), sponsored by the National Eye Institute. In these studies, participants were given high-dose antioxidant supplements, including Vitamin E, Vitamin C, beta-carotene (or later, lutein and zeaxanthin), zinc, and copper. The results showed that this combination could slow the progression of intermediate to advanced AMD but did not prevent the onset of AMD nor significantly benefit people with early-stage disease. Importantly, it is unclear how much of the benefit was due to Vitamin E versus the other components in the formula. Evidence for Vitamin E as a standalone supplement for eye health is limited and much weaker.

Current consensus from eye health organizations is that Vitamin E may play a supportive role as part of an antioxidant combination for specific populations at risk of advanced AMD, but there is insufficient evidence to recommend it broadly for eye health or for cataract prevention. Thus, the evidence supporting Vitamin E’s use for the eyes is modest and not definitive.

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