Evidence supporting the use of: Vitamin A (retinyl palmitate)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin A, particularly in the form of retinyl palmitate, is strongly supported by scientific evidence for its role in maintaining eye health. Vitamin A is an essential nutrient required for the formation of rhodopsin, a pigment in the retina that enables vision in low-light conditions. Deficiency in vitamin A is well documented as a leading cause of preventable blindness in children worldwide, and night blindness is one of the earliest symptoms. Numerous clinical studies and public health interventions have demonstrated that vitamin A supplementation can prevent and treat xerophthalmia (a spectrum of eye diseases caused by vitamin A deficiency), including Bitot’s spots, corneal ulcers, and ultimately, blindness. Both the World Health Organization (WHO) and the United States Institute of Medicine recognize the critical importance of vitamin A for ocular health.

Retinyl palmitate is a preformed (active) version of vitamin A that is efficiently absorbed and utilized by the body. Unlike plant-based provitamin A carotenoids (like beta-carotene), retinyl palmitate does not need to be converted in the body to be used for visual function. Thus, its use is scientifically validated for the prevention and treatment of vitamin A deficiency-related eye disorders. However, excessive supplementation of vitamin A can be toxic, so appropriate dosing is important.

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